Promethazine hydrochloride sleep

What are the side effects of Promethazine? The most common side effect of this medication is drowsiness, but it can also cause: Abnormal movements in your limbs Increased feelings of excitability Breathing problems Reduced production of white blood cells Reduced platelet count Allergic skin reactions Blood pressure changesThe pharmacy-only product contains the active ingredient promethazine hydrochloride, which blocks the action of histamine in the brain, "helping you drift off to sleep", Sanofi says. Promethazine has been used as a sedative for insomnia for "over 50 years" and "can start work within 20 minutes", the manufacturer says.AWilson32 Member. Tinnitus Since: 01/2016. Cause of Tinnitus: Earphone use. Have had it for 18 momths since getting T and helped me back into a normal sleep routine. However in the last week the effect appears to be wearing off. Was on a 50mg dose and then 75mg daily. AWilson32, Sep 14, 2017.Druginformer Identified Side Effects: Tremor, Fatigue, Feeling jittery, Nightmare, Sleep paralysis, Hallucination, Adverse drug reaction. Posted By Anonymous in askapatient.com on May 19, 2011 @ 12:00 am. " Side Effects: Nightmares, hallucinations, tremors, extreme fatigue Phenergan, at first, seemed like it would be the miracle drug I've ...Promethazine is used to treat several conditions, including allergies, motion sickness, nausea and vomiting, anxiety before surgery, and pain after surgery. It's also used as a sleep aid, including...Journal of Clinical Sleep Medicine, 9(6):559-566. Further reading. Buscemi, N., Vandermeer, B., Hooton, N., et al. (2005). The efficacy and safety of exogenous melatonin for primary sleep disorders: A meta-analysis. ... The promethazine hydrochloride injection also received a black box warning from the FDA in 2009 indicating that severe ...treatment of insomnia in adults Adults (including the elderly) and children over 10 years: 1 or 2 tablets (25 mg to 50 mg) taken at night. ... you are allergic to promethazine hydrochloride or any of the other ingredients in the tablets (listed in section 6). The signs of an allergic reaction include: a rash,It is a type of medication that is used to treat allergy symptoms, nausea, and vomiting. It can also act as a natural sleep aid. The street value for promethazine hydrochloride can vary depending on where you are purchasing it from. For example, in the United States, the average street price for promethazine hydrochloride ranges from $2-10 per ...Promethazine hydrochloride (HCl) is an antihistamine marketed under the brand names Phenergan and Pentazine. Promethazine HCl was approved by the U.S. Food and Drug Administration (FDA) in 1951, and is used to treat the following conditions: "Hay fever" or a stuffy runny nose from allergy. Watery, itchy eyes due to inhaled allergies and foods.There have been a number of cases of respiratory depression, sleep apnea, and SIDS in children receiving phenothiazine antihistamines at various weight-based dosages. The mechanism of this reaction is not yet known; therefore, promethazine should be used with extreme caution, if at all, in children with a family history of SIDS or sleep apnea ...Promethazine is often taken at bedtime or before meals. For motion sickness, promethazine is usually started within 1 hour before traveling. When used for surgery, promethazine is usually taken the night before the surgery. How often you take this medicine and the timing of your dose will depend on the condition being treated.To help you sleep, take promethazine 20 minutes before you go to bed. It normally takes about 30 minutes to work. To prevent motion sickness, take promethazine the night before a long journey or 1 to 2 hours before a short journey. Common side effects of promethazine include drowsiness, headaches, nightmares and feeling dizzy, restless or confused.Promethazine hydrochloride Promethazine hydrochloride Navigate to section Indications and dose Symptomatic relief of allergy such as hay fever and urticaria, Insomnia associated with urticaria and pruritus By mouth Child 2-4 years 5 mg twice daily, alternatively 5-15 mg once daily, dose to be taken at night. Child 5-9 yearsAWilson32 Member. Tinnitus Since: 01/2016. Cause of Tinnitus: Earphone use. Have had it for 18 momths since getting T and helped me back into a normal sleep routine. However in the last week the effect appears to be wearing off. Was on a 50mg dose and then 75mg daily. AWilson32, Sep 14, 2017.Phenergan (promethazine): Phenergan (promethazine) is an anti histamine and is sleep, inducing. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can helpPromethazine Hydrochloride with NDC 0641-0928 is a a human prescription drug product labeled by Hikma Pharmaceuticals Usa Inc.. The generic name of Promethazine Hydrochloride is promethazine hydrochloride. ... For sedation and relief of apprehension and to produce light sleep from which the patient can be easily aroused. Active treatment of ...It should. Take a few deep breaths and imagine yourself in a safe wonderful place surrounded by warmth and love and acceptance. Let all your troubles go and just feel your body getting heavy. Unclench your fists, stop shaking your foot, and put your worries on a shelf for tonight. Report / Delete Reply lynne82155 rossg1234 Posted 6 years ago5 hours ago · Phenazopyridine HCl tablets contain the following inactive ingredients: carnauba wax, croscarmellose sodium, hypromellose, magnesium ondansetron GENITOURINARY prochlorperazine promethazine scopolamine transdermal benzonatate (except NDCs^ 69336012615, 69499032915) BETA AGONISTS, § SHORT ACTING ATI MEDICATION TEMPLATE- Benzonatate. When taking promethazine for sleep, take it about 20 to 30 minutes before going to bed. If you do not feel the effects, do not take another dose. Don't chew the tablets, as this can affect the size of the dosage. Instead, swallow the tablets whole with a glass of water. Don't take more than the recommended dose.It is a type of medication that is used to treat allergy symptoms, nausea, and vomiting. It can also act as a natural sleep aid. The street value for promethazine hydrochloride can vary depending on where you are purchasing it from. For example, in the United States, the average street price for promethazine hydrochloride ranges from $2-10 per ...1 Name of Medicine. Promethazine hydrochloride. 2 Qualitative and Quantitative Composition. Allersoothe tablets contain 10 mg or 25 mg promethazine hydrochloride. Allersoothe Elixir contains 5 mg/5 mL promethazine hydrochloride. Excipients with known effect. Tablets: Lactose monohydrate. Elixir: Sodium benzoate.This product relieves apprehension and induces a quiet sleep from which the patient can be easily aroused. Administration of 12.5 to 25 mg promethazine hydrochloride by the oral route or by rectal suppository at bedtime will provide sedation in children. Adults usually require 25 to 50 mg for nighttime, presurgical, or obstetrical sedation.5 hours ago · It contains codeine phosphate & promethazine hydrochloride. It blocks the effects of a certain natural substance (histamine), which causes allergy symptoms. This preparation is a clear syrup with yellow color and pineapple menthol odor, containing promethazine hydrochloride 6. The syrup will be taken to the lab an analyzed. This product relieves apprehension and induces a quiet sleep from which the patient can be easily aroused. Administration of 12.5 to 25 mg promethazine HCl by rectal suppository at bedtime will provide sedation in children. Adults usually require 25 to 50 mg for nighttime, presurgical, or obstetrical sedation.Promethazine hydrochloride Promethazine hydrochloride Navigate to section Indications and dose Symptomatic relief of allergy such as hay fever and urticaria, Insomnia associated with urticaria and pruritus By mouth Child 2-4 years 5 mg twice daily, alternatively 5-15 mg once daily, dose to be taken at night. Child 5-9 yearsAdult: As promethazine hydrochloride supp: 25 mg at bedtime, or 12.5 mg before meals and at bedtime if necessary. Usual range: 6.25-12.5 mg tid. Dosage must be adjusted to the lowest effective dose to relieve symptoms. Adult: As promethazine hydrochloride supp: 25-50 mg for night-time, pre-surgical or obstetric sedation.Promethazine hydrochloride. All Photos (1) Synonym(s): 10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride. Empirical Formula (Hill Notation): C 17 H 20 N 2 S ... Slow-wave sleep and rapid eye movement (or paradoxical) sleep have been found in mammals, birds and lizards, but it is unclear whether these neuronal signatures are found in non ...a low seizure threshold closed angle glaucoma decreased lung function stenosing peptic ulcer a narrowing of the opening between the stomach and the small intestine blockage of the stomach or...It is mostly used for allergies and nausea, but can also be used for sedation because medical procedures and sleep difficulties. I am finding that I feel sick, headache and generalised tiredness (really a hangover effect). I plan to go and see my gp next week, if I have no improvement by then. Oct 17, 2013 #4 K Kas_Can_Fly MyPTSD ProPromethazine hydrochloride is a racemic compound; the molecular formula is C17H20N2S • HCl and its molecular weight is 320.88. Promethazine hydrochloride occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. It is freely soluble in water and soluble in alcohol.National Center for Biotechnology Information. 8600 Rockville Pike, Bethesda, MD, 20894 USA. Contact. Policies. FOIA. HHS Vulnerability Disclosure. National Library of Medicine. National Institutes of Health. Department of Health and Human Services.Promethazine hydrochloride tablets, USP may lead to potentially fatal respiratory depression. Use of promethazine hydrochloride tablets, USP in patients with compromised respiratory function (e.g., COPD, sleep apnea) should be avoided. Lower Seizure Threshold Promethazine hydrochloride tablets, USP may lower seizure threshold.Promethazine hydrochloride tablets, USP in 12.5 to 25 mg doses for children and 50 mg doses for adults the night before surgery relieves apprehension and produces a quiet sleep. For preoperative medication, children require doses of 0.5 mg per pound of body weight in combination with an appropriately reduced dose of narcotic or barbiturate and ... This product relieves apprehension and induces a quiet sleep from which the patient can be easily aroused. Administration of 12.5 to 25 mg promethazine HCl by rectal suppository at bedtime will provide sedation in children. Adults usually require 25 to 50 mg for nighttime, presurgical, or obstetrical sedation. My Resource. must have my share in the conversation if you are speaking of music. Copyright Tektronix, Inc. might at least have preserved the respectability of his ... 1 Name of Medicine. Promethazine hydrochloride. 2 Qualitative and Quantitative Composition. Allersoothe tablets contain 10 mg or 25 mg promethazine hydrochloride. Allersoothe Elixir contains 5 mg/5 mL promethazine hydrochloride. Excipients with known effect. Tablets: Lactose monohydrate. Elixir: Sodium benzoate.Promethazine HCl (marketed as Phenergan) Information. Adverse reactions or quality problems experienced with the use of this product may be reported to the FDA's MedWatch Adverse Event Reporting ...The active ingredient in Phenergan is promethazine hydrochloride, which is an antihistamine that belongs to a group of medicines known as phenothiazines. When you have an allergic reaction, your body creates a natural substance called histamine. ... Phenergan can be used as a short-term remedy for insomnia, or difficulty sleeping, helping you ...Promethazine is used to treat several conditions, including allergies, motion sickness, nausea and vomiting, anxiety before surgery, and pain after surgery. It's also used as a sleep aid, including...This product relieves apprehension and induces a quiet sleep from which the patient can be easily aroused. Administration of 12.5 to 25 mg promethazine HCl by rectal suppository at bedtime will provide sedation in children. Adults usually require 25 to 50 mg for nighttime, presurgical, or obstetrical sedation. There have been a number of cases of respiratory depression, sleep apnea, and SIDS in children receiving phenothiazine antihistamines at various weight-based dosages. The mechanism of this reaction is not yet known; therefore, promethazine should be used with extreme caution, if at all, in children with a family history of SIDS or sleep apnea ...Promethazine hydrochloride is a phenothiazine derivative which possesses antihistaminic, sedative, antimotion-sickness, antiemetic, and anticholinergic effects. Promethazine is a competitive H ... For sedation and relief of apprehension and to produce light sleep from which the patient can be easily aroused. 5. Active treatment of motion sickness.There have been a number of cases of respiratory depression, sleep apnea, and SIDS in children receiving phenothiazine antihistamines at various weight-based dosages. The mechanism of this reaction is not yet known; therefore, promethazine should be used with extreme caution, if at all, in children with a family history of SIDS or sleep apnea ...5 hours ago · It contains codeine phosphate & promethazine hydrochloride. It blocks the effects of a certain natural substance (histamine), which causes allergy symptoms. This preparation is a clear syrup with yellow color and pineapple menthol odor, containing promethazine hydrochloride 6. The syrup will be taken to the lab an analyzed. Promethazine hydrochloride tablets, USP may lead to potentially fatal respiratory depression. Use of promethazine hydrochloride tablets, USP in patients with compromised respiratory function (e.g., COPD, sleep apnea) should be avoided. Lower Seizure Threshold Promethazine hydrochloride tablets, USP may lower seizure threshold.1 Name of Medicine. Promethazine hydrochloride. 2 Qualitative and Quantitative Composition. Allersoothe tablets contain 10 mg or 25 mg promethazine hydrochloride. Allersoothe Elixir contains 5 mg/5 mL promethazine hydrochloride. Excipients with known effect. Tablets: Lactose monohydrate. Elixir: Sodium benzoate.Promethazine HCl (marketed as Phenergan) Information. Adverse reactions or quality problems experienced with the use of this product may be reported to the FDA's MedWatch Adverse Event Reporting ...Promethazine in the highest dose, 200 mg, gave drowsiness and hangover effects in 14 nights out of 20. The REM-depressing effect of promethazine together with its relatively weak REM-rebound effect may explain its value in the treatment of withdrawal symptoms following abuse of alcohol and barbiturates. Publication types Clinical TrialBarcode = 7489 Promethazine HCl Syrup Plain Rx Only promethazine hcl syrup plain (Promethazine HCl Syrup Plain) syrup [ANI Pharmaceuticals, Inc.] Rx Only . ... Sedation in both children and adults, as well as relief of apprehension and production of light sleep from . which the patient can be easily aroused.Promethazine is a first-generation antihistamine and antiemetic used to treat allergies, insomnia, and nausea.It was once widely used as an antipsychotic, although it is generally not used for this purpose now. [citation needed] It has approximately 1/10 the antipsychotic strength of chlorpromazine.[irrelevant citation] It may also help with some symptoms associated with the common cold and ...Phenergan with Codeine (promethazine and codeine) is a combination of an antihistamine, sedative, anti-nausea drug, cough suppressant, pain reliever, and cough suppressant used to treat common cold symptoms and cough. Common side effects of Phenergan with Codeine include dizziness, restlessness, inability to sleep, palpitations, and changes in muscle tone and more.Histamine in psychiatry: promethazine as a sedative anticholinergic - Volume 25 Issue 4. Histamine is a small positively charged molecule derived from the amino acid histidine, originating from ergot, the fungal putrefaction of protein in rye ().It was identified as biologically active by one of the founding fathers of British pharmacology, Henry Dale: working with Patrick Laidlaw in the ...Promethazine HCl/ Phenergan. Thread starter MarlieeB; Start date Sep 3, 2014; Tags hcl phenergan promethazine sleep thinking M. MarlieeB Former member. Joined Jan 15, 2013 ... (for sleep management to help control other symptoms) Just ensure you take the prescribed dose and look after yourself!! Last edited: Sep 3, 2014.Promethazine is a first-generation antihistamine and antiemetic used to treat allergies, insomnia, and nausea.It was once widely used as an antipsychotic, although it is generally not used for this purpose now. [citation needed] It has approximately 1/10 the antipsychotic strength of chlorpromazine.[irrelevant citation] It may also help with some symptoms associated with the common cold and ...Promethazine hydrochloride works by blocking histamine, the substance produced by your body during an allergic reaction. Yet, it also has an impact on other substances in the brain, such as acetylcholine. ... Taking promethazine for sleep problems: Commonly, Night Nurse capsules contain 20 milligrams (mg) of promethazine, which is often enough ...Short term relief of insomnia (difficulty sleeping) in adults. Short term use as a sedative for children over 5 years old. ... Promethazine hydrochloride is a type of medicine called a phenothiazine, which works by blocking a chemical called histamine that your body produces during an allergic reaction. This medicine also works directly on the ...Promethazine Codeine Each 5 ML contains: Promethazine hydrochloride 6.25 mg; codeine phosphate 10 mg. Alcohol 7%. Indication: Cough Suppressant Dosage Form: Syrup Validity: 2 years Strength 200 mg 16 oz, 32 oz. ... trouble breathing, or sleep apnea, high levels of carbon dioxide in the blood, stomach or bowel. block or narrowing.1 Name of Medicine. Promethazine hydrochloride. 2 Qualitative and Quantitative Composition. Allersoothe tablets contain 10 mg or 25 mg promethazine hydrochloride. Allersoothe Elixir contains 5 mg/5 mL promethazine hydrochloride. Excipients with known effect. Tablets: Lactose monohydrate. Elixir: Sodium benzoate.NAME 1.1 Substance Promethazine (INN, 1992) Promethazine hydrochloride (BAN, 1994; USAN, 1994 ... Respiratory depression, sleep apnoea and sudden infant death syndrome (SIDS) have occurred in a number of infants or young children who were receiving usual doses of promethazine. (Kahn & Blum, 1979 and 1982; Kahn et al., 1985). ...It should. Take a few deep breaths and imagine yourself in a safe wonderful place surrounded by warmth and love and acceptance. Let all your troubles go and just feel your body getting heavy. Unclench your fists, stop shaking your foot, and put your worries on a shelf for tonight. Report / Delete Reply lynne82155 rossg1234 Posted 6 years agoDec 13, 2021 · Promethazine is often taken at bedtime or before meals. For motion sickness, promethazine is usually started within 1 hour before traveling. When used for surgery, promethazine is usually taken the night before the surgery. How often you take this medicine and the timing of your dose will depend on the condition being treated. Promethazine HCl Oral Solution may lead to potentially fatal respiratory depression. Use of Promethazine HCl Oral Solution in patients with compromised respiratory func-tion (e.g. COPD, sleep apnea) should be avoided. Lower Seizure Threshold Promethazine HCl Oral Solution may lower seizure threshold. It should be used with cautionPromethazine hydrochloride is a phenothiazine derivative which possesses antihistaminic, sedative, antimotion-sickness, antiemetic, and anticholinergic effects. Promethazine is a competitive H ... For sedation and relief of apprehension and to produce light sleep from which the patient can be easily aroused. 5. Active treatment of motion sickness.The name of your medicine is Promethazine Hydrochloride 10 mg Tablets, (referred to as Promethazine in this leaflet). It belongs to a group of medicines known as phenothiazines, and works by blocking a substance called histamine that your body makes during an allergic reaction. It also works directly on the brain to help you feel more relaxed. National Center for Biotechnology Information. 8600 Rockville Pike, Bethesda, MD, 20894 USA. Contact. Policies. FOIA. HHS Vulnerability Disclosure. National Library of Medicine. National Institutes of Health. Department of Health and Human Services.Clinical studies indicate that promethazine can depress the arousal and normal respiratory mechanisms in normal infants during sleep, and may result in sudden death in apnea-prone infants (Kahn et al, 1985). This observation has been confirmed in sleep studies in neonatal piglets, where promethazine decreased the spontaneous occurrence of swallowing and arousal, and increased the occurrence of ...Promethazine HCl/ Phenergan. Thread starter MarlieeB; Start date Sep 3, 2014; Tags hcl phenergan promethazine sleep thinking M. MarlieeB Former member. Joined Jan 15, 2013 ... (for sleep management to help control other symptoms) Just ensure you take the prescribed dose and look after yourself!! Last edited: Sep 3, 2014.Strength: 20mg. Rated 9.6 /10 based upon 103 customer reviews. At Pharmica, we aspire to provide exceptional patient care and take great pride in our customer service. Read 103 of our independent customer feedback for Sominex Sleep Aid (Promethazine) below or visit Feefo, Trustpilot and Google directly to see all our reviews.Descriptions. Promethazine is used to relieve or prevent the symptoms of hay fever, allergic conjunctivitis (inflammation of the eye), and other types of allergy or allergic reactions. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery ...Journal of Clinical Sleep Medicine, 9(6):559-566. Further reading. Buscemi, N., Vandermeer, B., Hooton, N., et al. (2005). The efficacy and safety of exogenous melatonin for primary sleep disorders: A meta-analysis. ... The promethazine hydrochloride injection also received a black box warning from the FDA in 2009 indicating that severe ...For sedation, allergic rhinitis, urticaria and insomnia. As an adjunct in pre-operative sedation in surgery and obstetrics. As a paediatric sedative; Pharmacology. ... Promethazine Hydrochloride may enhance the action of any anticholinergic agent, tricyclic antidepressant, sedative or hypnotic, Alcohol should be avoided during drug treatment. ...5 hours ago · It contains codeine phosphate & promethazine hydrochloride. It blocks the effects of a certain natural substance (histamine), which causes allergy symptoms. This preparation is a clear syrup with yellow color and pineapple menthol odor, containing promethazine hydrochloride 6. The syrup will be taken to the lab an analyzed. Promethazine HCl/ Phenergan. Thread starter MarlieeB; Start date Sep 3, 2014; Tags hcl phenergan promethazine sleep thinking M. MarlieeB Former member. Joined Jan 15, 2013 ... (for sleep management to help control other symptoms) Just ensure you take the prescribed dose and look after yourself!! Last edited: Sep 3, 2014.Promethazine hydrochloride is a racemic compound; the molecular formula is C17H20N2S • HCl and its molecular weight is 320.88. Promethazine hydrochloride occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. It is freely soluble in water and soluble in alcohol.This is the most common sleep disorder. Sleep apnea - a breathing disorder in which you stop breathing for 10 seconds or more during sleep Restless leg syndrome (RLS) - a tingling or prickly sensation in your legs, along with a powerful urge to move them Hypersomnia - being unable to stay awake during the day. NAME 1.1 Substance Promethazine (INN, 1992) Promethazine hydrochloride (BAN, 1994; USAN, 1994 ... Respiratory depression, sleep apnoea and sudden infant death syndrome (SIDS) have occurred in a number of infants or young children who were receiving usual doses of promethazine. (Kahn & Blum, 1979 and 1982; Kahn et al., 1985). ...Promethazine is a first-generation antihistamine and antiemetic used to treat allergies, insomnia, and nausea.It was once widely used as an antipsychotic, although it is generally not used for this purpose now. [citation needed] It has approximately 1/10 the antipsychotic strength of chlorpromazine.[irrelevant citation] It may also help with some symptoms associated with the common cold and ...Strength: 20mg. Rated 9.6 /10 based upon 103 customer reviews. At Pharmica, we aspire to provide exceptional patient care and take great pride in our customer service. Read 103 of our independent customer feedback for Sominex Sleep Aid (Promethazine) below or visit Feefo, Trustpilot and Google directly to see all our reviews.Answer (1 of 5): Everything can, if the dose is high enough. Promethazine hydrochloride has been lethal in humans at 3.5 mg/kg orally (about 250 mg for a 70 kg adult), but from animal tests, the human equivalent that gives a 50/50 chance of death would be between 1700 and 4000 mg for a 70 kg per...Promethazine hydrochloride tablets, USP may lead to potentially fatal respiratory depression. Use of promethazine hydrochloride tablets, USP in patients with compromised respiratory function (e.g., COPD, sleep apnea) should be avoided. Lower Seizure Threshold Promethazine hydrochloride tablets, USP may lower seizure threshold.Adult: As promethazine hydrochloride supp: 25 mg at bedtime, or 12.5 mg before meals and at bedtime if necessary. Usual range: 6.25-12.5 mg tid. Dosage must be adjusted to the lowest effective dose to relieve symptoms. Adult: As promethazine hydrochloride supp: 25-50 mg for night-time, pre-surgical or obstetric sedation.Promethazine hydrochloride works by blocking histamine, the substance produced by your body during an allergic reaction. Yet, it also has an impact on other substances in the brain, such as acetylcholine. ... Taking promethazine for sleep problems: Commonly, Night Nurse capsules contain 20 milligrams (mg) of promethazine, which is often enough ...Pre- and Postoperative Use Promethazine HCl in 12.5- to 25-mg doses for children and 50-mg doses for adults the night before surgery relieves apprehension and produces a quiet sleep. For preoperative medication children require doses of 0.5 mg per pound of body weight in combination with an appropriately reduced dose of narcotic or barbiturate ... It is mostly used for allergies and nausea, but can also be used for sedation because medical procedures and sleep difficulties. I am finding that I feel sick, headache and generalised tiredness (really a hangover effect). I plan to go and see my gp next week, if I have no improvement by then. Oct 17, 2013 #4 K Kas_Can_Fly MyPTSD ProIt is a type of medication that is used to treat allergy symptoms, nausea, and vomiting. It can also act as a natural sleep aid. The street value for promethazine hydrochloride can vary depending on where you are purchasing it from. For example, in the United States, the average street price for promethazine hydrochloride ranges from $2-10 per ...Adult: As promethazine hydrochloride supp: 25 mg at bedtime, or 12.5 mg before meals and at bedtime if necessary. Usual range: 6.25-12.5 mg tid. Dosage must be adjusted to the lowest effective dose to relieve symptoms. Adult: As promethazine hydrochloride supp: 25-50 mg for night-time, pre-surgical or obstetric sedation.Promethazine hydrochloride Promethazine hydrochloride Navigate to section Indications and dose Symptomatic relief of allergy such as hay fever and urticaria, Insomnia associated with urticaria and pruritus By mouth Child 2-4 years 5 mg twice daily, alternatively 5-15 mg once daily, dose to be taken at night. Child 5-9 yearsStrength: 20mg. Rated 9.6 /10 based upon 103 customer reviews. At Pharmica, we aspire to provide exceptional patient care and take great pride in our customer service. Read 103 of our independent customer feedback for Sominex Sleep Aid (Promethazine) below or visit Feefo, Trustpilot and Google directly to see all our reviews.Promethazine HCl, a phenothiazine derivative, ... Sedation This product relieves apprehension and induces a quiet sleep from which the patient can be easily aroused. Administration of 12.5 to 25 mg promethazine HCl by rectal suppository at bedtime will provide sedation in children. Adults usually require 25 to 50 mg for nighttime, presurgical ...Promethazine HCl Oral Solution may lead to potentially fatal respiratory depression. Use of Promethazine HCl Oral Solution in patients with compromised respiratory func-tion (e.g. COPD, sleep apnea) should be avoided. Lower Seizure Threshold Promethazine HCl Oral Solution may lower seizure threshold. It should be used with cautionPromethazine hydrochloride is a phenothiazine derivative which possesses antihistaminic, sedative, antimotion-sickness, antiemetic, and anticholinergic effects. Promethazine is a competitive H ... For sedation and relief of apprehension and to produce light sleep from which the patient can be easily aroused. 5. Active treatment of motion sickness.There have been a number of cases of respiratory depression, sleep apnea, and SIDS in children receiving phenothiazine antihistamines at various weight-based dosages. The mechanism of this reaction is not yet known; therefore, promethazine should be used with extreme caution, if at all, in children with a family history of SIDS or sleep apnea ...Promethazine hydrochloride is a racemic compound; the molecular formula is C17H20N2S • HCl and its molecular weight is 320.88. Promethazine hydrochloride occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. It is freely soluble in water and soluble in alcohol. 10l_2ttl